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  • Genotoxicity Testing: Unlocking the Future Safety Assessment Op

    Genotoxicity testing refers to the evaluation of detrimental effects of chemical or physical agents on the genetic processes and related hereditary material of living cells. On the other hand, mutagenicity is the process of inducing irreversible and transmissible alterations in the genetic material...
  • Adeno-Associated Viral Vectors: Unlocking the Future Opportunit

    Given the potential of gene therapies in targeting the underlying cause of a disease at cellular level, the demand for such therapies has increased considerably over the past few years.   Currently, more than 285 gene therapies are being evaluated in different phases of clinical development. ...
  • Modular Construction – Retrofitting Conventional Buildings

    Shifting construction away from traditional sites and into factories could dramatically change the way we build.   Will off-site builds bolster construction this time around? Over the years, construction has straggled behind other sectors in terms of efficiency. Off-site builds or modular con...
  • Long-Acting Drug Delivery: A Novel Pharmacological Strategy to

      LADD has emerged as the novel and advanced drug delivery system which manipulate the dosing regimen of the drug in the body in order to sustain its therapeutic level.   Over the last two decades, the pharmaceutical industry has observed a paradigm shift from conventional drug delivery...
  • Digital Therapies: The “Digital Pills” of current generation

    As per United Nation’s report, the current global population stands at around 8 billion and expected to reach 9 billion by the end of 2030. This increase in population is accompanied with a rise in the incidence of several chronic disease indications. In fact, as per a report published by Nat...
  • Medical Device Coatings and Modification Technologies

    Over the past 50 years, the medical device industry has seen several notable developments. In fact, according to the World Health Organization (WHO), presently, around two million medical devices are available across the globe. Further, since 2020, the Food and Drug Administration (FDA) has approve...
  • Demand for Outsourcing Biologics Fill Finish Services

    The increasing demand for biologics has led to an increasing need for production capacity, which is characterized by high quality standards.   Although, it is a challenging field, outsourcing has emerged as a promising segment, especially for drug product manufacturing and aseptic fill / fini...
  • The Future of Dentistry: Dental 3D Printing

    3D printing, also known as additive manufacturing, is a method of producing 3-dimensional objects layer-by-layer, using a computer aided design.   Owing to its ability to print complex models using a wide range of materials, 3D printing has applications across various industries, including de...
  • Bioavailability Enhancement Technologies

    A study conducted on terminated drug development projects revealed that majority of the drug candidates fail in early drug development phases, due to the problems associated with their pharmacokinetic profiles, ADME properties and toxicity-related issues.   Moreover, it is a well-established ...
  • Liposomes Development: Service Providers Landscape

    In recent years, liposomes have garnered significant interest of researchers, as well as industry players, owing to their potential in diagnosis and treatment of various diseases, with a focus on delivering drugs and genetic material.   Liposomes are small, artificial and lipid-based bilayere...
  • mRNA Synthesis: Manufacturing Process of Modern Revolutionary M

    Messenger ribonucleic acid (mRNA) is a single-stranded molecule, which carries coding sequence and plays a prominent role in protein synthesis.   It transfers genetic information form to DNA to ribosomes, a specialized structure, or organelle, which decodes genetic information into a protein....
  • TIL Therapies: A New Paradigm in Cancer Treatment

      Till date, several clinical trials have demonstrated the efficacy and therapeutic superiority (over conventional treatment options) of TIL-based therapies.   Modified tumor-infiltrating lymphocytes or TIL therapies have emerged as a viable and potent option to selectively eradicate th...
  • Viral Clearance and Viral Testing Services

    Considering the rising demand for biologics, innovators in the biopharmaceutical industry are constantly exploring avenues that would enable them to overcome the existing technical and operational challenges related to viral-clearance and testing for timely approval of biologics.   Outso...
  • Artificial Intelligence (AI) In Oncology: Current Scenario and

    In the last decade, the popularity of AI has grown invariably. It has made a considerable impact in the medical sector and oncologic treatment as well, due to a surge in electronic data, breakthroughs in technological infrastructure and groundbreaking research in deep learning neural networks. &nbs...
  • Rising Demand for Medical Devices CROs

    Over the past decade, numerous scientific and technological breakthroughs in the medical device CROs industry have resulted in an accelerated pace of research and innovation within this domain. Further, the demand for advanced and minimally invasive medical devices has been augmented due to the inc...
  • SARM1 Inhibitors: A Novel Approach Against Neurodegenerative Di

    Presently, several industry and non-industry stakeholders are evaluating SARM1 inhibitors as potential therapeutic agents for the treatment of neurological disorders across various preclinical studies and early stages of clinical development, worldwide.   Given the encouraging research outcom...
  • TCR Therapies: An Emerging Therapeutic Modality

      Structurally, TCR is a heterodimer comprising of two different polypeptide chains, namely the α-chain and β-chain.   Modified T-cell receptors or TCR therapies is an emerging class of adoptive therapy that employs genetically modified lymphocytes to target specific tumor ma...
  • Cell Therapy – The Revolutionary Therapeutic Modality: All Set

    The American Society of Gene and Cell Therapy (ASGCT) defines cell therapy as a therapeutic modality that involves the administration of either normal or modified cells to patients for the treatment of various diseases.   In this form of therapy, patients are injected with living and intact h...
  • 4D Bioprinting Market: Key Trends

    4D bioprinting refers to the addition of a fourth dimension that enables 3D printed structures to change their shape with time with the help of smart biomaterials, which have the tendency to morph in the presence of stimuli (such as, heat, light, electricity, magnetic energy, stress). &nb...
  • Applications of Blockchain in Various Sectors

    The term blockchain refers to the way it stores transaction data in blocks that are linked to form a chain. Since every entry is stored as a block on the chain, the length of the chain increases as more transactions are recorded and stored. The digital ledger technology was...
  • Monkeypox: Disease Overview, Transmission and Diagnosis

    Monkeypox is a viral disease, which is usually transmitted to humans from animals. The disease is known to have symptoms similar to those observed in smallpox patients, although it is considered to be clinically less severe. In recent years, monkey pox has emerged as a prominent orthopox virus affe...
  • CAR-T Cell Therapies

      Amidst the active initiatives undertaken to develop more targeted anti-cancer therapies, CAR-T therapies have emerged as a promising option, given their ability to eradicate tumor cells from the body with minimal treatment-related side effects.   Further, CAR-T cell therapies, relativ...
  • Exploring How Artificial Intelligence Is Transforming Digital P

    Digital pathology is a transformative technology that has enabled pathologists to make the shift from visual inspection of tissue samples to automated image analysis.   With the advent of AI, pathologists are now benefiting from computerized image analysis software that can draw conclusions a...
  • The smart pharmaceutical and healthcare labels market

    In order to overcome the limitations and challenges related to counterfeit drugs, researchers and industry stakeholders are gradually adopting smart pharmaceutical and healthcare labels, which offer multiple benefits over conventional labels. Roots Analysis has announced the addition of “Smar...
  • The TCR-based therapy market

    Given the recent approval of a TCR-based therapy, industry stakeholders have initiated several R&D efforts focused on evaluating the potential of such therapy candidates against various disease indications Roots Analysis has announced the addition of “Global TCR-based Therapy Market (2nd Edi...
  • Growing demand for Medical devices, Novel coatings

    Over the past 50 years, the medical device industry has seen several notable developments. In fact, the use of biomedical devices, such as medical implants, surgical instruments, and prostheses has increased substantially over the time.   Cardioverter defibrillators, prosthetic hips and knees...
  • The mRNA synthesis and manufacturing market

    Given the current technical and operational challenges associated with the manufacturing of mRNA-based products, innovators in the biopharmaceutical industry are increasingly relying on the mRNA synthesis and contract manufacturing service providers. Roots Analysis has announced the addition of &ld...
  • LONG-ACTING DRUG DELIVERY TECHNOLOGIES AND SERVICES

    Long-acting drug delivery has emerged as the novel and advanced drug delivery system which manipulate the dosing regimen of the drug in the body in order to sustain its therapeutic level.   Over the last two decades, the pharmaceutical industry has observed a paradigm shift from conventional ...
  • TIL-BASED THERAPY: AN INNOVATIVE WAY TO TREAT SOLID TUMORS

    Modified tumor-infiltrating lymphocytes (TIL)-based interventions have emerged as a viable and potent option to selectively eradicate the tumor population, with minimal side effects. Till date, several clinical trials have demonstrated the efficacy and therapeutic superiority (over conventional tre...
  • DIGITAL THERAPEUTICS

    Digital therapeutics are clinically validated applications / software / online programs that have demonstrated the capability to facilitate positive outcomes when used in the prevention / treatment / management of diseases / clinical conditions.   Digital Therapeutics, popularly known as DTx,...